893 research outputs found

    A Path Model of SCCT Applied to the Rural Appalachian Community

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    The current study investigates the relationship between variables in the Social Cognitive Career Theory model as applies to rural Appalachia. A path model was conducted in order to see which variables are significantly related, as well as which paths differ from the hypothesized model, in this population. Results suggest that there is a direct effect of college going self-efficacy (CGSES) on college planning behaviors (CPB), as well as direct paths from barriers and postsecondary supports (PSS) to pursuing a education after high school. Indirect effects were also found from PSS and Barriers to CPB through CGSES. Surprisingly, no direct path was found between college outcome expectations and any of the other variables, with the exception of PSS. Implications and limitations of the study suggest that future literature should investigate how these distinctions in the model may affect the theory within the rural Appalachian population, as well as collectivist and/or rural populations more generally

    Direct valuation of a community\u27s amenities

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    A Generalized Theory of Varying Alpha

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    In this paper, we formulate a generalization of the simple Bekenstein-Sandvik-Barrow-Magueijo (BSBM) theory of varying alpha by allowing the coupling constant, \omega, for the corresponding scalar field \psi\ to depend on \psi. We focus on the situation where \omega\ is exponential in \psi\ and find the late-time behaviours that occur in matter-dominated and dark-energy dominated cosmologies. We also consider the situation when the background expansion scale factor of the universe evolves in proportion to an arbitrary power of the cosmic time. We find the conditions under which the fine structure `constant' increases with time, as in the BSBM theory, and establish a cosmic no-hair behaviour for accelerating universes. We also find the conditions under which the fine structure `constant' can decrease with time and compare the whole family of models with astronomical data from quasar absorption spectra.Comment: 25 pages, 6 figures. Minor corrections and clarifications added. Final section on spatial variations removed so that the paper focuses exclusively on time-variatio

    Expanding Access to Naloxone: A Review of Distribution Strategies

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    Amidst an ongoing opioid crisis that claimed 47,600 lives in 2017, increasing the availability of the rescue medication naloxone is a high priority. Naloxone reverses an opioid overdose when given intranasally or intramuscularly. But to be effective, naloxone must be available at the time of overdose. Naloxone distribution to laypeople can save a life when first responders are not immediately available, or when people witnessing overdoses are unwilling or unable to call 911. Naloxone is increasingly available through some pharmacies under a standing order; however, even when available, cost and stigma barriers persist. This Issue Brief reviews recent evidence on the outcomes and cost-effectiveness of naloxone distribution strategies in community, pharmacy, and other health care settings

    Matematika i društvena pravda - Kako djeca shvaćaju i prikazuju nejednakost

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    Društvena pravda možda se čini presloženom temom za šestogodišnjake i sedmogodišnjake, pogotovo ako je želimo iskazati kroz matematički koncept. Kako uopće djeca razumiju društvenu pravdu? (Allen, 1997.; Boutte, 2008.

    Effects of negative energy balance on liver gene and protein expression during the early postpartum period and its impacts on dairy cow fertility

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    End of project reportNegative energy balance (NEB) is a severe metabolic affecting high yielding dairy cows early post partum with both concurrent and latent negative effects on cow fertility as well as on milk production and cow health. The seasonal nature of Irish dairy production necessitates high cow fertility and a compact spring calving pattern in order to maximise grass utilisation. Poor dairy cow reproductive performance currently costs the Irish cattle industry in excess of €400 million annually. High milk yields have been associated with lower reproductive efficiency, and it has been suggested that this effect is probably mediated through its effects on the energy balance of the cow during lactation. The modern high genetic merit dairy cow prioritises nutrient supply towards milk production in early lactation and this demand takes precedence over the provision of optimal conditions for reproduction. In this study we used the bovine Affymetrix 23,000 gene microarray, which contains the most comprehensive set of bovine genes to be assembled and provides a means of investigating the modifying influences of energy balance on liver gene expression. Cows in severe negative energy balance (SNEB) in early lactation showed altered hepatic gene expression in metabolic processes as well as a down regulation of the insulin-like growth factor (IGF) system, where insulin like growth factor-1 (IGF-1), growth hormone receptor variant 1A (GHR1A) and insulin-like growth factor binding protein-acid labile subunit (IGFBP-ALS) were down regulated compared to the cows in the moderate negative energy balance MNEB group, consistent with a five-fold reduction in systemic concentrations of IGF1 in the SNEB group.Cows in SNEB showed elevated expression of key genes involved in the inflammatory response such as interleukin-8 (IL-8). There was a down regulation of genes involved in cellular growth in SNEB cows and moreover a negative regulator of cellular proliferation (HGFIN) was up regulated in SNEB cows, which is likely to compromise adaptation and recovery from NEB. The puma method of analysis revealed that 417 genes were differentially regulated by EB (P<0.05), of these genes 190 were up-regulated while 227 were down-regulated, with 405 genes having known biological functions. From Ingenuity Pathway Analysis (IPA), lipid catabolism was found to be the process most affected by differences in EB status
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